大连医科大学第二临床学院导师：郑丰
[通讯方式]
办公电话：13365917598
电子邮件：fzheng63@163.com
[个人简述]
郑丰，二级教授，硕士及博士研究生导师；作为大学“其震工程”引进的高端人才，现担任大连医科大学医科院PI。在美国拥有独立领导的老年肾脏病研究室。研究工作多次得到美国国立研究院和国际糖尿病基金会的资助。在肾脏衰老的研究方面处于国际领先地位。共发表SCI文章70余篇，最高影响因子为30.7。目前有两项国家自然基金。2015年发表著作《老年肾脏临床重点与难点》。获得两项中国人民解放军科技进步二等奖，（第一完成人一项，第二完成人一项），国家科技进步二等奖一项（第五完成人），和中华医学科技一等奖一项（第五完成人）。同时为中国医师学会肾脏专业委员会及中国生理学会肾脏专业委员会委员。
[科研工作]
在研课题： 国家自然科学基金面上项目（2014），TNF介导的信号在肾小球微血管和大血管衰老中的作用。
文章发表情况：（以下均为第一作者或者通讯作者，近5年SCI文章）
1. Gao X, Huang L, Grosjean F, Esposito V, Wu J, Fu L, Hu H, Tan J, He C, Gray S, Jain MK, Zheng F (co-correspondence author), Mei C: Low protein diet supplemented with ketoacids reduces the severity of renal disease in 5/6 nephrectomized rats: A role for KLF15. Kidney Int, 79:987-96, 2011 IF=8.563
2. Yu Y, Wang Y, Zhou LN, Zheng F: ARB treatment protects against the decrease in endothelial progenitor cells in remnant kidney model. Am J Nephrol, 33:550-7, 2011 IF=2.669
3. Wu J, Guan T, Grosjean F, Xiong H, Striker GE, Zheng F: Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice. Lab Invest, 91:1459-71, 2011 IF=3.676
4. Chen J, Yu ZH, Huang J, Lin HK, Gao X, Zheng F: A simple automated device for children renal biopsy: Advantage in obtaining more tissue . J Clin Pathol, 64:1029-31, 2011 IF=2.915
5. Huang QJ, Lan FH, Wang Z, Zheng F: Akt2 suppresses GAPDH mediated apoptosis via phosphorylating GAPDH at tyr157 and inhibiting its nuclear translocation. J Bio Chem, 286:42211-20, 2011 IF=4.573
6. Lupia E, Zheng F (co-first author), Grosjean F, Tack I, Doublier S, Elliot S, Vlassara V, Striker G: Pentosan polysulfate inhibits atherosclerosis in watanabe heritable hyperlipidemic rabbits: Differential modulation of metalloproteinase 2 and 9. Lab Invest, 92:236-45, 2012 IF=3.676
7. Zhang R, Zheng ZY, Lin J, Qu L, Zheng F: The continual presence of C3d but not IgG glomerular capillary deposition in stage I idiopathic membranous nephropathy in patients receiving corticosteroid treatment. Diagnostic Pathology, 7:109， 2012 IF=2.597
8. Lu J, Wang Q, Huang L, Dong H, Lin L, Lin N, Zheng F （Co-correspondence）, Tan J: Palmitate Causes Endoplasmic Reticulum Stress and Apoptosis in Human Mesenchymal Stem Cells: Prevention by AMPK Activator． Endocrinology，153:5275-84， 2012 IF=4.503
9. Esposito V, Grosjean F, Tan J, Chen J, Xiong H, Striker G, Zheng F: Chop deficiency results in elevated lipopolysaccharide induced inflammation and kidney injury. Am J Physiol, 302：F440-50,2013 IF=3.248
10. Guo J, Zou Y, Wu Z, Wu W, Xu Z, Hu H, Huang L, Dong H, Chen J, Lu J, Fu Y, Wang J, Ma Y, Chen X, He F, Yang S, Liao L, Chen J, Zheng F （Co-correspondence）, Tan J： Protective effects of mesenchymal stromal cells on adriamycin-induced minimal change nephrotic syndrome in rats and possible mechanisms. Cytotherapy 16(4):471-84，2014 IF=3.29
11. Wang X, Lin Y, Lan F, Yu Y, Ouyang X, Wang X, Huang Q, Wang L, Tan J, Zheng F：A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer. J Cancer Res Clin Oncol. 140(8):1399-411， 2014 IF=3.081
12. Wang H, Geng DM, Zhang LM, Wu XY, Zheng F：Echocardiography detection of fetal ventricular aneurysm: A report of three cases. J Clin Ultrasound. 2014 Jul 28. doi: 10.1002/jcu.22211. IF=0.691
13. Zheng Z and Zheng F: Immune cells and Diabetic nephropathy. J Diabetes Res. 2016(3):1-10 IF=2.164
14. Jian Chen, Guangming Chen, Daping Xiao, Weihua Peng, Guoqing Yu, Yueyong Lin, and Feng Zheng : Continuous venovenous hemofiltration decreases mortality and ameliorates acute lung injury in canine model of severe salt water drowning. Scand J Trauma Resusc Emerg Med. 2016 24: 40. Published online 2016 Mar 31. doi: 10.1186/s13049-016-0224-5PMCID IF=2.025
15. Zhang Y, Chen J, Zheng Z, Zheng F：HBV associated acute postinfectious glomerulonephritis. Plos One. 2016. In Press IF=3.234
[教育背景]
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